ABSTRACT
Background and aim: the purpose of present study was Evaluate the effect of vitamin D supplementation on mortality and intubation rate in COVID-19 patients Method:all articles published in international databases such as PubMed, Scopus, Science Direct, Embase between January 2019 and March 2022 included. 95% confidence interval on risk ratio (RR) were done with fixed effect model and Mantel-Haenszel method. Meta-analysis of data collected from selected studies was performed using STATA.V16 software. Result: full text of 31 articles was reviewed;finally, eight articles entered the analysis. Risk ratio of Effect on mortality and intubation rate between Vitamin D and standard-of-care regarding was -0.09 (RR;95% CI (-0.28, 0.10), p=0.36) and -0.25 (RR;95% CI (-0.59, 0.08), p=0.14). Conclusion: According to the meta-analysis, vitamin D administration is not effective on low intubation rate and reduce mortality rate of Covid-19 patients.
ABSTRACT
The aim of this study was to evaluate the effects of vitamin D supplements on mortality and intubation rates in patients with CVD19. Patients with coronary heart disease who take enough vitamin D have a 52 percent lower risk of dying than people with vitamin D deficiency, according to a new study. Research has shown that lowering vitamin D3 levels increases the risk of death in patients with severe dementia.Vitamin D is a hormone produced by the skin when exposed to sunlight. The point to be made is that there are differences of opinion in the world about the side effects of vitamin D deficiency, but what is certain. According to experiments conducted in our country, we are facing a severe deficiency of vitamin D among the people, especially among postmenopausal women, and according to the results of research, most Iranians are deficient in vitamin D. The best way to increase immunity is to use natural foods to get vitamins and minerals.In the corona pandemic, the role of vitamin D in boosting immunity, getting COVID-19, hospitalization and mortality has always been debated.Cross-sectio nal studies on the role of vitamin D in reducing the incidence, hospitalization and even death of Covid-19 in different countries show a significant relationship between serum vitamin D levels and the severity of COVID-19 and mortality from the disease. This association is probably due to the effects of vitamin D on the immune response to this infection. The results of cross-sectional studies show that countries such as Spain and Italy, which have the highest rates of vitamin D deficiency, have the highest rates of COVID morbidity and mortality.In contrast, northern European countries, which had higher serum levels of vitamin D due to food fortification, also reported lower rates.
ABSTRACT
Awareness of the effects of SARS-CoV-2 infection outside the airways can be important in the management of patients with underlying disease. Common signs and symptoms that persist over time include fatigue, shortness of breath, coughing, joint pain, and chest pain. Other long-term signs and symptoms may include muscle aches or headaches, rapid or rapid heartbeat, loss of smell or taste, memory problems, difficulty concentrating or sleeping, rashes, and hair loss. The results of studies show that adolescents are much less likely to develop lung problems due to coronavirus infection than others. In addition, the lungs of young people who have recovered from Covid-19 disease appear to be functioning as before. The researchers concluded that the corona virus did not affect adolescents' lung function in the long run.In addition, the coronavirus did not even affect the lung capacity of Covid-19 patients with asthma The results of studies show that the lung function of these people after recovery from Covid-19 disease was the same as before and did not change.The results of another similar study show that Covid-19 disease will not adversely affect the lung function of children and adolescents, as this group of people recover much faster than others and experience a shorter course of the disease.The results of this review article show that the consequences of Covid-19 disease are not limited to the lungs, but can go beyond and affect organs other than the lungs.